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Complete information for PYCARD gene (Protein Coding), PYD And CARD Domain Containing, including: function, proteins, disorders, pathways, orthologs, . PYCARD, often referred to as ASC is a protein that in humans is encoded by the PYCARD gene. It is localized mainly in the nucleus of monocytes and. UniProtKB - Q9ULZ3 (ASC_HUMAN) In breast tumorigenesis, methylation-mediated silencing may affect genes and proteins that act as positive mediators of cell death. Caspase recruitment domain-containing protein 5.
Functions as key mediator in apoptosis and inflammation. Promotes caspase- mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a . 6 days ago This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain. 15 May Pycard PYD and CARD domain containing [ (house mouse)] (AIA) through apoptosis-associated speck-like Pycard protein (ASC)-dependent.
Pycard Official Symbol: Pycard and Name: PYD and CARD domain containing [ Mus musculus (house mouse)] Other Aliases: A21Rik, Asc, CARD5. () cloned and characterized ASC, which they termed TMS1. Martinon et al. ( ) determined that ASC, which they termed PYCARD, shares the N-terminal. PYCARD (PYD and CARD domain containing), Authors: Jeffrey H Dunn, Mayumi Fujita. Published in: Atlas Genet Cytogenet Oncol Haematol. Summary of PYCARD (ASC, CARD5, TMS-1) expression in human tissue. Nuclear and cytoplasmic expression in several tissues, most abundant in subsets of. HGNC approved symbol report for the gene PYCARD (HGNC_ID).
PYCARD Polyclonal Antibody from Invitrogen for Western Blot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry and ELISA applications. PHENOTYPE No data available. DISEASE ASSOCIATED WITH pycard HUMAN ORTHOLOGNo data available. GENE ONTOLOGY. Recombinant protein of human PYD and CARD domain containing (PYCARD), transcript variant 2. products PYCARD encodes the human gene, PYD and CARD domain containing. It may also be known as: Apoptosis-associated speck-like protein.